Sandeep Singh

Software Developer | Clinical Research | Machine learning & AI

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About Me

I am a Kent State University graduate (2021) with a Bachelor's degree in Biology and an Associate of Science degree. Currently, I work as a Software Developer in Clinical Research at the Cole Eye Institute, where I specialize in developing software tools for image analysis and post-surgical assessment.

I have designed and implemented specialized software solutions that support ophthalmic research. My software has played a key role in multiple research publications, abstracts and conference presentations.

I am passionate about leveraging my programming skills along with my biology background to drive innovation in image analysis.

Education

Jan 2022

Certificate in Phlebotomy

Independence Phlebotomy USA, Independence, OH

Aug 2016 - Dec 2021

Bachelor of Science: Biology

Kent State University, Kent, OH

Aug 2016 - Dec 2021

Associate of Science

Kent State University, Kent, OH

Programming Projects

Multimodal Alignment Software

Python
2024 - Present

Co-developed software for polynomial non-rigid co-registration across multiple imaging modalities with ROI window feature and annotation transfer system. Successfully implemented alignment for FAF, FA, Color fundus, and OCTA enface image combinations.

Lesion Measurement Tool

Python
2024 - Present

Developed tool for pre/post-treatment comparison of sarcoid lesions with interactive GUI and real-time threshold adjustment for lesion segmentation. Implemented red/green tinting for direct visualization of lesion changes.

Premacular Bursa Measurement

Python
2024 - Present

Developed measurement tool for quantifying premacular bursa dimensions on OCT slices with scaling solutions for accurate measurements. Implemented user-friendly interface for research use.

OCT Enface to B-scan Projection

Python
2025 - Present

Created custom software to generate enface images from B-scans with alignment system to register enface images with fluorescein angiography. Developed pathology annotation system that projects markings from enface view to corresponding b-scans.

Cardiovascular Risk Calculator

Python
2024 - Present

Contributed to the development of a novel risk assessment tool for cardiovascular events using ophthalmic imaging. Created models to generate binary vessel masks and artery/vein segmentation from fundus images.

Coronary Calcium Score Prediction

Python, Machine Learning
2024 - Present

Developed three-tier prediction system from fundus images: exact calcium score prediction, categorical classification (Low/Medium/High), and binary classification (Zero/Non-zero).

Surgical Efficiency Analyzer

Python, SAM2 (Meta)
2024 - Present

Integrated SAM2 model into custom GUI for automatic surgical instrument segmentation. Implemented X-Y plotting system to evaluate surgical movement efficiency with visualization tools for analysis.

Oxygen Concentration Predictor

Python
2025 - Present

Developing software to predict O2 concentration in blood vessels using color channel analysis. Created specialized algorithms for vascular oxygen level estimation with visualization tools for research presentation.

General Vessel Extraction Tool

Python, Deep Learning
2024 - Present

Created versatile model for accurate binary mask generation across various ophthalmic imaging modalities. Implemented adaptive algorithms to handle different image types and qualities.

Publications Timeline

2025
AAO Abstract

Ocular Candidiasis Screening Using LLMs

Antaki F, Arline AA, Bala S, Mohan N, Schulgit MJ, Bellanda VCF, Mahmoud M, Singh S, et al. Scalable and Automated Extraction of Clinical Features from Ocular Candidiasis Screening Consultations Using Large Language Models. AAO 2025. Abstract Id: 30082430.

2025
ASRS Abstract

Retinal Ischemic Perivascular Lesions Study

Delaney A, Singh S, et al. Screening for retinal ischemic perivascular lesions in patients undergoing cardiovascular assessment: A one-year outcome analysis. ASRS 2025 43rd Annual Scientific Meeting. Proposal.

2025
ASRS Abstract

OCT Angiography in Retinal Vasculitis

Mizuno Y, Singh S, et al. Optical coherence tomography angiography findings in retinal vasculitis. ASRS 2025 43rd Annual Scientific Meeting. Proposal.

2024
AAO Abstract

OCT and OCT-A in Cardiovascular Studies

Srivastava SK, Sharma S, Baynes KM, Singh S, et al. OCT and OCT-A of the Retina in Patients Undergoing Cardiovascular Studies: A Prospective Study. AAO 2024. Abstract 30079813.

2024
ARVO Abstract

Quantitative Anterior Chamber Cell Analysis

Sharma S, Hamden A, Chen C, Singh S, et al. Longitudinal quantitative anterior chamber cell analysis following Vamikibart intravitreal therapy in patients with uveitic macular edema from the DOVETAIL clinical trial. Invest Ophthalmol Vis Sci. 2024;65(7):3028.

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2024
ARVO Abstract

Ultra-Widefield Fluorescein Angiography Study

Singh S, Sharma S, Baynes K, et al. Imaging characteristics and clinical utility of full-dose vs quarter-dose ultra-widefield fluorescein angiography. Invest Ophthalmol Vis Sci. 2024;65(7):5959.

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2024
Journal Article

Ultrawidefield Fundus Fluorescein Angiography

Szigiato A, Sharma S, Singh S, et al. Imaging characteristics and clinical utility of half-dose versus full-dose ultrawidefield fundus fluorescein angiography. Ophthalmol Retina. 2024;8(10):981-986. doi:10.1016/j.oret.2024.04.024.

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2023
ARVO Abstract

Remote Assessment with OCT

Erwin C, Sharma S, McDonald MA, Singh S, et al. Remote assessment of patients with red eyes utilizing anterior segment optical coherence tomography – a pilot study. Invest Ophthalmol Vis Sci. 2023;64(8):3408.

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2023
ARVO Abstract

Ultra-Widefield Fluorescein Angiography Comparison

Szigiato A, Singh S, Mills M, et al. Imaging characteristics and clinical utility of half vs full dose ultra-widefield fluorescein angiography. Invest Ophthalmol Vis Sci. 2023;64(8):3730.

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2023
ARVO Abstract

Choroidal Vessel Thickness Study

Singh S, Mammo D, Baynes K, et al. The change in choroidal vessel thickness on ICG angiography in patients who underwent scleral windows for uveal effusion syndrome. Invest Ophthalmol Vis Sci. 2023;64(8):2084.

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